Are you passionate about science and want to contribute in developing groundbreaking cancer treatments? IO Biotech, a cutting-edge clinical-stage biotech company, is looking for an innovative Biomarker Scientist to help drive translational research in the tumor microenvironment. This is your chance to play a key role in shaping the future of immunomodulatory cancer therapies, all while working in a dynamic, fast-paced, and collaborative environment.

Based on-site in our state-of-the-art laboratories in Rockville, Maryland, you will report directly to the VP of Precision Medicine & Biomarkers.

Key responsibilities include, but are not limited to:

Planning and executing research on the feasibility, optimization, and qualification of clinical biomarker assays across multiple clinical trials
Performing hands-on tissue-based assays, including protocol development, assay optimization, validation, troubleshooting, and performance monitoring
Analyzing and interpret results, conduct meta-analyses, and apply appropriate statistical methods
Developing and applying bioinformatics pipelines to analyze complex biospecimen datasets.
Serving as the in-house subject matter expert on the tumor microenvironment using Nanostring, scRNAseq, multiplex immunofluorescence, and IHC technologies.
Collaborating with Clinical Operations, Data Science, and Preclinical teams, while contributing to corporate biomarker goals.
Preparing technical reports, summaries, and presentations, and communicate results effectively.
Drafting and adhering to Standard Operating Procedures (SOPs).
Maintaining accurate and complete electronic laboratory records in compliance with scientific and regulatory standards.
Performing various duties and responsibilities as assigned to support the team.

Qualifications And Skills

Ph.D. in immunology, cancer biology, or a related field, with 2+ years of relevant biotech/pharma industry experience
Strong expertise in scRNAseq, multiplex immunofluorescence, and/or spatial transcriptomics is essential
Proven experience in bioinformatics, with proficiency in R or other programming languages, and ability to handle multi-modal, high-dimensional translational data
Experience with HALO is a plus
Prior industry experience in clinical biomarker analytical testing is preferred
A collaborative team player with a positive, problem-solving mindset and strong attention to detail

What we offer:

The possibility to join a lean organization where contributions have an immediate impact and is acknowledged.
A global work environment
An informal working culture with room to bring ideas and initiatives to life.
Competitive salary and benefit package

Interviews may be conducted on an ongoing basis.

We look forward to receiving your application!

IO Biotech is a clinical-stage biopharmaceutical company pioneering the first-in-class investigational dual-action immune-modulating cancer vaccine with the goal of becoming the backbone of combination therapy for people with cancer. The Company’s T-win® vaccine platform is directed against the tumor microenvironment (TME) and is designed to stimulate T cells against tumor cells and the most important immune-suppressive cells in the TME. IO Biotech’s most advanced program for IO102-IO103 is currently in Phase 3 development.

IO Biotech

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Biomarker Scientist