Do you want to help us develop cutting-edge polymer-based nanoparticles for advanced drug delivery systems? Are you eager to contribute to a dynamic team environment where your expertise will be crucial to launching a new company? Then join us at The BioInnovation Institute (BII) at Nørrebro, where we are currently looking for an Analytical Chemist to play a key role in our company-creation program.
The mission of BII is to create new life science solutions to address unmet societal or health needs. At BII, we have established a program, Bio Studio, which aims to build life science start-ups based on world-class research. Bio Studio projects are three-year grant funded projects sourced from leading researchers employed at research institutions worldwide. The projects we admit combine scientific novelty, commercial viability, and the potential for significant societal and/or health impact. The goal of the projects is to create a viable start-up company based on the project within the three years.
BII aims to recruit a strong project team for each Bio Studio project, and it is expected that this team will form the core of the future start-up deriving from the project. Apart from establishing a solid Project Team, to be headed up by an Entrepreneur in Residence, BII provides a comprehensive network of industry, investors, and subject matter experts to support the projects.
Your Opportunity to Join BII’s Bio Studio Program!
We are launching an exciting new project focused on developing cutting-edge in-vivo drug delivery technology with specific applications in targeted gene delivery for oncology treatments. This innovative project has been initiated by highly renowned Principal Investigators from a leading Danish research organization and represents a significant opportunity to advance therapeutic approaches in cancer treatment.
As part of BII's Bio Studio program, this project aims to transform groundbreaking research into a viable startup company within a three-year timeframe. You will have the unique opportunity to work at the forefront of nanomedicine, collaborating with world-class scientists to develop polymeric nanoparticle technologies that could revolutionize how genetic material is delivered to target cells in cancer patients.
By joining our team, you will play an instrumental role in bringing this promising technology from laboratory concept to clinical application, with the potential to significantly impact cancer treatment paradigms and patient outcomes.
Your ownership of our mutual journey will be to:
- Design and synthesize polymer-based nanoparticles for gene delivery applications.
- Develop scalable synthesis and formulation methods to ensure reproducibility and efficiency.
- Optimize physicochemical properties (size, charge, stability) for enhanced immune cell transfection.
- Establish and perform analytical assays to characterize nanoparticles, including size distribution (DLS, TEM), surface charge (zeta potential), encapsulation efficiency, and release kinetics.
- Develop stability and degradation studies under physiological conditions.
- Collaborate with cell biologists to evaluate nanoparticle transfection efficiency in immune cells.
- Interpret in vitro and in vivo experimental data to refine nanoparticle formulations.
- Troubleshoot challenges related to cellular uptake and gene expression.
- Work closely with process development teams to scale up nanoparticle production under GMP conditions.
- Ensure compliance with regulatory guidelines for gene delivery products.
- Contribute to technology transfer, manufacturing process optimization, and regulatory documentation.
Your daily work and well-being will be shared directly with the Entrepreneur in Residence, but as a small community with close ties and bright minds, you should be prepared for many cross-functional and inspiring discussions that can help shape your work at BII.
Your Professional & Personal Qualifications
We're looking for a creative problem-solver who's passionate about developing innovative nanoparticle technologies. You thrive at the intersection of chemistry and biology, combining technical expertise with genuine curiosity. The ideal candidate enjoys tackling complex challenges in a collaborative environment and can translate scientific concepts into practical solutions. You're detail-oriented yet adaptable, ready to navigate the exciting journey from bench to bedside in a startup setting. Most importantly, you bring not just technical skills but also enthusiasm and a growth mindset as we build something meaningful together.
Besides this, you have:
- Ph.D. in Polymer Chemistry, Materials Science, Bio-nanotechnology, Pharmaceutical Sciences, or a related field. Alternatively, you have a master’s degree and significant industry experience
- Strong expertise in polymer synthesis and nanoparticle formulation techniques
- Hands-on experience with analytical methods such as DLS, TEM, HPLC, SEC, UV-Vis, and fluorescence spectroscopy
- Familiarity with cellular biology and gene delivery techniques (e.g., transfection, endosomal escape strategies)
- Understanding of biopharmaceutical manufacturing and regulatory aspects of nanoparticle-based therapeutics
- Fluent in English language oral and written
- Super user in the MS Office package
Preferred Experience:
We welcome candidates with experience in industrial settings, and worked with gene therapy, mRNA delivery, or nanomedicine. Familiarity with CMC requirements and GMP manufacturing would be valuable to our team. If you've worked in startup environments or have a talent for clearly presenting complex scientific concepts, these skills would complement our collaborative approach.
We value team members who are naturally curious about cancer biology, enjoy developing their skills, and can adapt to both independent and collaborative work. Our research environment is dynamic and offers opportunities to contribute meaningfully to innovative solutions.
Your Experience Working at BII
We offer a committed and professional workplace in which we emphasize ensuring that our colleagues thrive, are challenged, and have opportunities to develop their potential. A career at BII allows you to work with world-leading entrepreneurial scientists in a position where you will have a substantial chance to impact your job and the opportunity to develop your bio entrepreneurial skills.
BII invites you to become part of a vibrant and professional workplace with a chance to bring ideas to life and science to market for the benefit of society and human welfare.
Are you curious for more?
For more information, don't hesitate to contact Kåre Engkilde, Entrepreneur in Residence, via e-mail: ken@biostudio.dk or on the phone: +45 51840577. The deadline for applying for this job is 26/03/2025. However, we will hold interviews on a rolling basis and encourage you to send your application as soon as possible.
To apply, please submit your CV and cover letter by clicking on the “Apply now” button.
