Be the new Head of Modeling & Simulation
In a biotech company bonding to discover, design and develop innovative peptide-based medicines.
Currently, we are looking for a Head of modeling and simulations, who will get a unique opportunity to make an impact by establishing the department and setting the future strategic direction for PK/PD modeling and simulation at Zealand Pharma. If this sounds like you, and you are ready to take on a broad area of responsibilities with an independent attitude, you are a match for us.
Modeling & Simulation is a new Department within Pharmacokinetics, Immunogenicity and Bioanalytical Sciences under Research and Non-clinical Development. The Department will have the responsibilities to support clinical development projects and late phase research projects by setting the direction and drive execution of translational PK and PK/PD strategies. In addition, the Department will be responsible for building mathematical models and performing human PK and PD simulations to guide non-clinical and clinical study designs as well as regulatory discussions. The position is based in Søborg, Copenhagen.
Responsibilities
- Establish and lead the new Modeling & Simulation Department.
- Set the direction, define and drive execution of translational pharmacokinetics (PK) and pharmacodynamics (PK/PD) strategies to support clinical development and late-phase research projects.
- Develop and implement mathematical models to simulate human PK and PD, guiding non-clinical and clinical study designs.
- Perform human PK and PD simulations to inform regulatory interactions and submissions.
- Collaborate with clinical development teams to integrate modeling and simulation insights into project plans and decision-making processes.
- Oversee outsourced modeling and simulation activities, ensuring they meet quality standards and project requirements.
- Provide technical expertise and training to team members on PK/PD modeling and simulation techniques.
- Ensure high quality of reports and simulation outcomes presented to stakeholders, including senior management and regulatory bodies.
- Foster a collaborative environment within the department and with other teams to achieve project goals.
Candidate profile
- MSc degree or PhD within Pharmaceutical, Medical, Engineering, Statistical or Mathematical sciences or equivalent.
- At least 10 years of experience in modeling and simulation within pharma or biotech industry and a proven track record of leading successful projects.
- Comprehensive knowledge of pharmacokinetics (PK), including the processes of absorption, distribution, metabolism, and excretion of drugs.
- In-depth understanding of biology, physiology, and various regulatory mechanisms.
- Proficiency in simulation software (e.g. Phoenix WNL/NLME or similar)
- Strong analytical and problem-solving skills, with the ability to interpret complex data and develop accurate models.
- Excellent communication and presentation skills, capable of conveying technical information to non-technical stakeholders.
- Leadership and team management experience, with the ability to inspire and guide a diverse team.
- Knowledge of industry standards and best practices in modeling and simulation.
- Ability to work collaboratively in a multidisciplinary environment and manage multiple projects simultaneously.
Bonding to innovate
Our employees are fundamental to our success, and we continue to be able to attract and retain people with vast experience and talent. We have a unique culture, characterized by excellent teamwork and strong engagement across the organization.
Making bonds is at the core of everything we do. From discovering and developing the best new peptide drugs for patients, to engaging with our partners or connecting with each other.
We bond as a result of our entrepreneurial culture where our people are encouraged to pursue their ideas and turn them into reality. We are curious about each other’s knowledge and expertise.
We bond through curiosity and playfulness as a team, allowing ourselves to challenge common thinking and drive future innovation. Zealand Pharma is a place where everyone is heard and contributes to the success, we all want to experience.
The Zealand Pharma DNA builds on four values: (1) We are bold, (2) We empower people, (3) We work as one team, and (4) We can be trusted.
Let’s bond and be bold
We offer a combined compensation package which includes a base salary, pension, bonus, and a possibility to join our employee share program. We care about our employees’ well-being and offer health insurance, use of massage, fitness, and a range of social clubs and activities
To find out more about working at Zealand, visit https://www.zealandpharma.com/careers/zealand-as-a-workplace/
Interested? Please apply no later than March 17, 2025, or as soon as possible. The applications will be reviewed as they come in.
For further information, please contact Carsten Boye Knudsen, CKnudsen@zealandpharma.com / +45 5060 3614
About Zealand Pharma A/S
Zealand Pharma A/S (Nasdaq Copenhagen: ZEAL) ("Zealand") is a Danish biotechnology company on a mission to change lives with next generation peptide medicines. In our effort to reach our goals bonding is at the core of everything we do. Let it be discovering and developing the best new peptide drugs for patients, engaging with partners or connecting with each other. This has led to more than 10 drug candidates invented by Zealand having advanced into clinical development, of which two have reached the market. Zealand’s current pipeline of internal product candidates focus on specialty gastrointestinal and metabolic diseases. Additionally, the portfolio includes clinical license collaboration with Boehringer Ingelheim. Zealand is based in Copenhagen (Søborg), Denmark. For further information about the Company's business and activities, please visit www.zealandpharma.com or bond with us through LinkedIn.
