Join our Translational Biology team to help turn biological insight into tomorrow's therapies
Orbis Medicines is a pioneering Biotech company powered by our automated nGen chemistry platform and data-driven approach. We develop oral alternatives to injectable biologics and design drugs for hard-to-drug targets primarily in inflammation and immune-driven diseases.
As an experienced In Vitro Biologist, you will join our experienced Translational Biology team in Copenhagen. The team supports drug discovery from target selection through advanced hit and candidate selection with strong emphasis on disease understanding and building translational links. The work spans in vitro, ex vivo and in vivo studies and biomarker development to support FiH clinical trials. You will be part of an open and collaborative working environment where new ideas are welcomed.
About the role
In this hands-on role you will combine experimental work with project biology coordination, contributing directly to data generation while shaping pharmacology strategies and external collaborations.
Your key responsibilities will include
Experimental hands-on work
- Design, establish, and optimize disease-relevant cell-based assays to characterize function and potency of drug candidates
- Perform and interpret critical experiments, particularly during assay setup, troubleshooting, and at key decision points
- Ensure data quality, robustness, and biological relevance of in vitro datasets
Scientific & Translational leadership
- Lead in vitro pharmacology efforts within discovery projects and define assay strategies that support translational understanding and go/no-go decisions
- Contribute deep understanding of disease biology and cellular mechanisms to guide target selection and project strategy
- Communicate complex scientific data clearly to multidisciplinary stakeholders
CRO & External collaboration
- Identify, evaluate, and recommend relevant expert CRO’s and collaboration partners for assay and model development
- Oversee CRO-generated data packages, providing scientific direction, critical review, and integration into internal project decisions
Innovation & Collaboration
- Identify and implement new assay technologies, platforms, and experimental approaches that strengthen translational confidence
- Collaborate closely with Screening Biology, DMPK and project teams to ensure alignment across discovery stages
Your skills and expertise
- A Ph.D. in biology, biomedicine, or a related field
- +5 years of industry experience in Pharma or Biotech
- Strong track record in drug discovery and early development.
- Proven expertise in cell-based assay development, optimization, and troubleshooting across multiple assay modalities (e.g. functional assays, ligand-based assays, flow cytometry) and a keen interest in lab-based work
- Scientific background in immunology, chronic inflammatory diseases, and/or cardiometabolic diseases.
- Demonstrated ability to balance hands-on experimental work with scientific leadership and external oversight
- Experience with design and interpretation of in vivo pharmacology studies using disease-relevant animal models is an advantage
As a person you must be motivated by working hands-on in the laboratory enjoying the combination of experimental work with scientific problem-solving. You are proactive, collaborative, and have a solution-oriented mindset with strong self-leadership.
You thrive in a fast-moving, innovative biotech environment and it is key that you are able to communicate clearly across disciplines and seniority levels including the ability to present complex data to diverse audiences.
Contact and application
Please apply via the website.
If you have any questions about the role or the process please contact Talent Acquisition Partner Mia Danielsen (part of DEDENROTH) Phone: +45 26178142 / Email: mia.danielsen@orbismedicines.com
