About Hemab
Hemab Therapeutics is a clinical-stage biotechnology company committed to transforming care for people with serious bleeding and thrombotic disorders. At Hemab, we're redefining how bleeding and thrombotic disorders are understood and treated. Our goal: become the ultimate clotting company through patient-centric innovation and engagement. With headquarters in Boston and Copenhagen, we cultivate an agile environment where curiosity, creativity, and data-driven insights fuel success.
We seek an innovative colleague who will challenge conventional thinking about how biotech companies advocate for patients and drive systemic change for underserved communities.
The Opportunity – HMB-002 and von Willebrand Disease
HMB-002 is a novel antibody therapy in development for von Willebrand disease (VWD) — the most common bleeding disorder in the world, affecting patients worldwide yet still lacking convenient, consistent, and accessible treatment options. This program is advancing in the clinic with the goal of bringing a first-in-class subcutaneous therapy to patients who have long waited for better solutions.
The Asset Lead for HMB-002 will have the unique opportunity to shape this program from its current early stage through late-stage clinical development and beyond — helping define how Hemab will change the treatment landscape for people with VWD.
Role Purpose
The Asset Lead for HMB-002 is a pivotal role as the strategic integrator and champion for the program, accountable for translating scientific opportunity into clinical and commercial reality. The AL ensures cross-functional alignment, drives execution, and maximizes value through patient impact, in line with corporate objectives.
The AL owns the asset’s Integrated Development Plan (IDP), chairs the Asset Core Team, sets the asset ambition and drives execution of strategy through to major milestones. They will represent HMB-002 at the Management Team (MT) and Board of Directors (BoD) as required, ensuring risks, decisions, actions, and opportunities are clearly articulated.
While the strategic direction, goals, and resources are set by the Management Team (MT), the AL and Asset Team are empowered to develop and deliver strategies within that frame — shaping the “how” of execution, surfacing opportunities, and proactively identifying risks or trade-offs for MT consideration.
This role requires a leader who can balance enterprise alignment with asset-level initiative, managing the natural tension between corporate strategy and bottom-up program/indication strategy.
Key Responsibilities
Strategic Integration
- Translate Management Team defined corporate goals and priorities into actionable development strategies for HMB-002.
- Ensure all planning and execution aligns with corporate strategy, while championing for the resources and expertise required to achieve corporate objectives.
- Develop strategies that optimize scientific, regulatory, clinical, and commercial opportunities.
Cross-Functional Leadership
- Chair the Asset Core Team, empowering function leads to contribute expertise while driving alignment toward asset goals.
- Maintain a high ambition level for HMB-002, ensuring the team remains anchored on global patient impact and long-term value creation.
- Partner with sub team leads to integrate functional strategies into overall program plans.
- Scale commercialization (access and medical) input appropriately by stage of development.
- Foster a culture of accountability, collaboration, and transparent decision-making across functions.
Decision-Making, Governance and Communication
- Lead issue identification and resolution within the team’s scope of authority.
- Surface risks, trade-offs, and opportunities that require MT decision-making.
- Represent HMB-002 at MT and BoD forums, presenting recommendations and highlighting implications for current corporate objectives.
- Prepare and present concise Dashboards for MT decision-making (monthly) and deeper 360 reviews (biannual).
- Represent Hemab externally as needed (partners, investors, advocacy groups), always in alignment with the Asset Core Team and MT direction.
Execution and Accountability
- Own delivery of the Integrated Development Plan (IDP) and Dashboard, ensuring they remain the single source of deep knowledge and truth for the asset.
- Track execution against goals and ensure readiness for development milestones.
- Ensure knowledge, learnings, and best practices are systematically captured and shared across the organization.
- Drive a high level of ambition, aligning the team to “what it takes to get there” for maximal patient impact.
Candidate Profile
- Enterprise Mindset: Thinks beyond the product; understands how each program fits into Hemab’s overall corporate strategy; drives toward the “bigger picture” for maximal patient benefit.
- Resilient strategist: Skilled at translating enterprise strategies into practical execution, while spotting opportunities for incremental value creation; Can set bold direction while operating lean; Decisive in ambiguity.
- Strong communicator and influencer; Natural tension manager: Navigates the balance between corporate directives and asset-level autonomy, knowing when to escalate versus when to resolve internally; First-rate communication, facilitation and influence ability.
- Operational pragmatist: Outcome-oriented and able to inspire cross-functional collaboration; Thrives in uncertainty and pushes teams to deliver; Creatively solves problems, sees opportunities, and drives a sense of urgency for patient benefit.
- Scientific & commercialization integrator: Balances deep scientific understanding with market, patient, and access insights to drive holistic strategies.
- Passion for helping patients: Motivated to develop transformative treatments for patients in need; Energized by patient focus and makes personal commitments to high performance and results.
- Culture Advocate: Embraces and lives Hemab’s core company values and facilitates operating principles to further evolve and strengthen a strong and sustainable work culture.
Key Performance Indicators (KPIs)
- Quality, clarity, and currency of IDP and Dashboard.
- Timely achievement of asset milestones aligned with corporate goals.
- Effectiveness of MT engagement (clear decision requests, risk escalation).
- Cross-functional alignment and team engagement.
- Successful integration of functional perspectives to optimize asset value.
Qualifications
- Relevant advanced degrees and training; financial fluency is a plus.
- 12+ years of experience in biotech/pharma development (rare disease, hematology preferred) across multiple phases; Registration experience is a plus.
- Strong understanding of end-to-end drug development and regulatory pathways.
- Demonstrated ability to lead cross-functional teams without heavy hierarchy.
- Track record of effective stakeholder engagement (internal MT, external partners, BoD, or investors).
