Overview:
We are seeking a highly motivated and organized individual to join our dynamic team in a hybrid Research Associate (RA) / Lab Manager (Contractor) position. The contract is expected to last 6 months. This is an exciting opportunity to contribute to cutting-edge mRNA-based therapeutics while also playing a key role in the smooth operation of our lab facilities. You will be part of a rapidly growing startup working on novel programmable mRNA technologies to target diseases at the cellular level.
Key Responsibilities:
Research Associate Responsibilities (80%):
- Assist in cloning of high-content plasmid libraries and NGS sample prep for high-throughput screens, ensuring timely and efficient workflows.
- Design and perform molecular biology experiments, including plasmid cloning and sample preparation for RNA sequencing (RNAseq, RNA amplicon sequencing).
- Normalize plasmids and prepare new stocks and aliquots of common plasmids for ongoing experiments.
- Perform nucleic acid extraction, RT-qPCR, dPCR, and other molecular characterization assays.
- Collaborate with team members to analyze data and present findings in group meetings.
- Maintain comprehensive, organized lab notebooks and experiment documentation.
Lab Management Responsibilities (20%):
- Oversee the scheduling and maintenance of laboratory equipment, ensuring proper calibration and functionality.
- Ensure laboratory equipment is in optimal condition (e.g., MiSeq sequencer, Attune flow cytometer).
- Manage inventory and ordering of laboratory consumables, ensuring stocks are adequately replenished.
- Prepare media for tissue culture (TC) and oversee other common laboratory preparations.
- Perform routine autoclaving of water and other necessary materials.
- Manage incoming shipments, including picking up packages from the loading dock, un-boxing, and organizing the lab space.
- Maintain accurate records of lab activities, inventory, and equipment status.
Qualifications:
- B.S. or M.S. in Biology, Bioengineering, Genetics, or related field.
- 5+ years of laboratory experience (academic or industry), with a strong foundation in molecular biology techniques.
- Strong organizational and multitasking skills, with an ability to maintain efficient lab operations and manage competing priorities.
- Familiarity with maintaining lab equipment, inventory systems, and ordering procedures.
- Excellent communication skills with the ability to present scientific data clearly and concisely.
- Positive, proactive, and collaborative team player with the ability to work independently.
Preferred Qualifications:
- Experience with flow-cytometry highly preferred
- Experience in cloning, plasmid preparation, and sample prep for RNAseq.
- Experience with high-content pooled libraries
- Experience with mammalian tissue culture, including BSL2 practices, transfection, and reporter assays.
- Prior experience with lab management, inventory control, and maintaining lab safety protocols.
- Familiarity with lentiviral production or mRNA-based production systems.
How to Apply:
We offer a competitive salary, comprehensive benefits, and the chance to work with an innovative, passionate team in a fast-paced startup environment. If you are excited to contribute to groundbreaking science and play an integral role in lab operations, we encourage you to apply by filling out the form at Dover.
